An overview of the projects funded from the funding line "Key Projects" can be found here.
Applications can be submitted at any time.
The Foundation’s aim with this funding measure is to find projects that have the potential to lead to fundamental discoveries that are groundbreaking for an entire field of research. This could be, for example:
- evidence of a causal connection that was previously lacking
- testing of a previously non-existent or unworkable hypothesis
- questioning of a previously generally accepted theory
- a “proof of principle” or a “first-in-man” examination of an innovative intervention approach,
- a clinical trial that has the potential to significantly transform guidelines (with the exception of phase III pharmaceutical trials)
- answering a new, fundamental question in an already established cohort
It is in the nature of going beyond the boundaries of previous limits of knowledge that such key projects can often not be assigned to any particular field or any thematically defined call for applications.
Addressees Eligible to Apply
Applications can be made by scientists who have gained international recognition in their area of research and who have had outstanding publications in relevant fields. The applicants should provide convincing evidence that their work group is particularly suited – also in the competitive international context – to solving the problem at hand through the interplay between expertise, preparatory work or even infrastructure.
Both human and material resources may be applied for as necessary and scientifically justified for implementation of the planned project. The funds shall be allocated in a two-stage procedure. Prior to the time-consuming formulation of a full application, a draft proposal should be submitted first. The topicality and potential of the project idea as a key project shall be evaluated based on this draft.
Project managers of an EKFS funding project that is currently ongoing shall only be eligible to make a new application after completion and publication of the results of that project.
Submitting the Paper of the Month:
We invite all project managers, fellowship recipients and members of graduate study programs to submit their publications that have emerged from funding as Paper of the Month. You can find more information here. You can find an overview of the Paper of the Month here.
2023
Key Project: "PROTamine Application in patients underGOing tRAnScatheter aortic valve replacement (PROTAGORAS)"
A brief description can be found here.
A brief description can be found here.
Key Project: "Kombinationstherapie von Natürlichen Killerzellen mit dem tri-spezifischen Antikörper- Derivat 33-16-123 (KT-1) zur Behandlung der Akuten Myeloischen Leukämie"
A brief description can be found here.
A brief description can be found here.
2022
A brief description can be found on our website in the menu Currently Funded Projects.
Pre-clinical evaluation of kidney engineering to prevent organ rejection in a large animal model
Refined locoregional genome editing to treat Duchenne muscular dystrophy.
SPLASH Studie "Sterotactic Cisternal Lavage Therapy in Patients with Aneurysmal Subarachnoid Hemorrhage with Urokinase and Nimodipine for the Prevention of Secondary Brain Injury. A Randomized Controlled Trial"
Stellenwert der katheterbasierten Ablationsbehandlung von Vorhofflimmern als mortalitäts- und morbiditätssenkende Therapie bei Patientinnen und Patienten mit terminaler Herzinsuffizienz vor oder während Listung zur Herztransplantation
Hauptantragstellende: Prof. Dr. Christian Sohns, Prof. Dr. Philipp Sommer, Dr. Vanessa Sciacca
Eine Kurzbeschreibung finden Sie auf unserer Website im Menü aktuelle Förderungen.
Eine Kurzbeschreibung finden Sie auf unserer Website im Menü aktuelle Förderungen.
A deadly liaison between proteins and RNA – how partners become enemies
Defining proteostasis differences between immortal pluripotent stem cells and their neuronal counterparts to ameliorate amyotrophic lateral sclerosis
A brief description can be found on our website in the menu Currently Funded Projects.
A brief description can be found on our website in the menu Currently Funded Projects.
Personalised immunotherapy of cholangiocarcinoma targeting fusion-specific neoepitopes
2021
A brief description can be found on our website in the menu Currently Funded Projects.
A brief description can be found on our website in the menu Currently Funded Projects.
A brief description can be found on our website in the menu Currently Funded Projects.
A brief description can be found on our website in the menu Currently Funded Projects.
A brief description can be found on our website in the menu Currently Funded Projects.
2020
A brief description can be found on our website in the menu Currently Funded Projects.
Key project: "Omission of sentinel lymph node biopsy in triple-negative and HER2-positive breast cancer patients with radiologic and pathologic complete response in the breast after neoadjuvant systemic therapy: a single-arm, prospective surgical trial (EUBREASR-01 trial)" (2020)
Here you can get further information.
A brief description can be found on our website in the menu Currently Funded Projects.
Here you can get further information.
A brief description can be found on our website in the menu Currently Funded Projects.
Key project: "Monogenic CD33 deficiency as cause of pediatric inflammatory bowel disease – A model to explore mechanisms and therapeutic targets for inflammatory and hematological disorders" (2021)
A brief description can be found on our website in the menu Currently Funded Projects.
A brief description can be found on our website in the menu Currently Funded Projects.
A brief description can be found on our website in the menu Currently Funded Projects.
2019
Key project: "Monitoring von Therapieeffekten und Nachweis minimaler Resterkrankung (MRD) bei der akuten myeloischen Leukämie (AML) des Erwachsenen mit DNMT3A Mutation im Rahmen innovativer Studienkonzepte der AMLSG (AMLSG 09-09, AMLSG 12-09 und ALMSG 16-10)" (2019)
Here you can get further information.
A brief description can be found on our website in the menu Currently Funded Projects.
Key project: "Inducing blood stage immunity by repeated Plasmodium falciparum sporozoite infection" (2019)