The aim is to develop improved diagnostic procedures and tailored management strategies for movement disorders. The scientists hypothesize that impaired neurodevelopment, due to gene alterations, contributes to the development of the diseases that are in the focus of the project. The team will combine modern DNA-analysis methods with studies of supragenomic layers to identify a comprehensive view of disease-driving molecular alterations. Integrating multicenter collaborations and using computational algorithms, they will discover neurodevelopmental disease networks and gain a better understanding of targets for treatment. Cell models will validate our discoveries. All results will be evaluated in terms of translatability to the clinics. 

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