The aim of this study is to increase the viability of adipocytes after autologous transplantation in order to reduce the resorption rate of the transplant. Due to the application of the angiogenetic hormone leptin the perfusion of the transplanted tissue shall be enhanced and hence the viability of the transplanted adipocytes shall be improved. 

Inguinal fat tissue is transplanted autologously into a dorsal skinfold chamber in mice. In the study group leptin is added at day 3, 7 and 10 after transplantation to the graft, the control animals are treated with saline solution only. The dorsal skinfold model allows for repetitive, intra vital microscopic analysis of the perfusion and the morphology of the adipocytes over a period of 15 days after transplantation.
 

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