Tumours in the brain are often difficult or poorly treatable. The reasons for this are the position in a crucial area of our bodies as well as molecular and structural characteristics of the tumours. In addition, changes of the tumours during treatment often reduces the effectiveness of therapies.     The sum of all factors which are limiting common treatments is referred to as drug resistance. Research into these factors as well as overcoming resistance is the main objective of the Heidelberg Research College for Neurooncology. 

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