Natur + Medizin
Frankfurt am Main, 16.04.2024. Insektenschutz aus Tausendfüßer-Sekret, Schwangerschaftstest per Krallenfrosch-Substanzen, Krebstherapie mit Hilfe eines Meeresschwamms – was verblüffend klingt, gibt es wirklich: Menschen und auch Tiere nutzen zahlreiche Naturstoffe für ihre Gesundheit. Die neue Dauerausstellung „Natur + Medizin“ im 2. Obergeschoss des Senckenberg Naturmuseums Frankfurt gibt ab 18. April Einblick in die erstaunliche Vielfalt dieser Wirkstoffe aus dem Reich der Pilze, Flechten, Bakterien, Pflanzen und Tiere und ihren medizinischen Nutzen.
Image-based therapy monitoring in glioma patients: Evaluation of quantitative MRI data and Deep Learning
For doctors specializing in brain tumors, it is difficult and time-consuming to assess whether a tumor is growing or if changes are caused by therapy. To determine this, they often have to rely on the temporal course or supplementary and scarcely available tests such as FET PET. A method utilizing quantitative MRI imaging and Deep Learning could help improve therapy and treatment monitoring. This research project aims to develop such a method.
Effects of LRRK2-mediated RAB hyperphosphorylation on the autophagic clearance of mitochondria
Mutations in the LRRK2 gene are the most common genetic cause of Parkinson's disease and lead to increased phosphorylation of RAB proteins by inducing hyperactivity of the LRRK2 enzyme. However, the mechanism by which RAB hyperphosphorylation may contribute to the pathogenesis of Parkinson’s disease is still unclear.
Characterization of Extracorporeal Membrane Oxygenation Induced Coaguloapathy
For many decades, changes in blood coagulation have been recognized to occur during treatment with a (heart) lung machines (ECMO), yet the underlying mechanisms are not well understood. Changes in blood coagulation may clinically manifest both by "blood clots" such as thromboembolism, e.g., in the form of strokes, as well as by a bleeding tendency, e.g., in the form of cerebral or pulmonary haemorrhage. These complications may negatively affect the treatment outcome and in some cases even be the reason for death.