Lentiviral vector-mediated gene therapy to treat hearing and balance loss patients

Project partner:
Prof. Dr. Michael Morgan
Dr. Juliane Schott
Prof. Dr. Hildegard Büning
John W. Hadden II, CEO of ViroCell Biologics Ltd. (London, UK)
Prof. Farzin Farzaneh, CSO of ViroCell Biologics Ltd. (London, UK)

Collaboration partners:
Prof. Dr. med. Athanasia Warnecke, Medizinische Hochschule Hannover
Prof. Dr. Hinrich Staecker, University of Kansas (USA)

Preclinical development of a new Slack activator for treatment of histamine-independent and chronic itch

Pruritus (itching) is an unpleasant sensation that evokes the desire to scratch. Similar to acute pain, acute pruritus serves as an important protective mechanism to recognize potentially harmful stimuli. However, chronic pruritus (i.e. persisting for more than 6 weeks) usually has no useful function and can cause great suffering to patients.