One of the most common symptoms of "Long-COVID" is fatigue, i.e. persistent exhaustion on a mental or physical level. The team explores the yet unclear psychological and neurobiological processes that might contribute to the subjective experience of fatigue. To do this, they use a computer task in which people learn (mental level) whether their bodily efforts (physical level) are rewarded and how these processes interact. Using mathematical models and functional MRI, they describe behavior and brain activity during the task. In addition, the team will collect blood samples to test how these processes relate to immune activation. With this research, the scientists hope to expand knowledge about fatigue and thereby also contribute to the development of therapies.
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