Brain
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Topography and Plasticity of the cortical microstructure in ALS characterized using 7 Tesla MRI

Institution: Medical Department, Otto-von-Guericke University Magdeburg
Applicant: Esther Kühn
Funding line:
First and Second Applications
Research methods
Research methods
(© Esther Kühn)

Novel imaging technology (7 Tesla MRI) allows the description of cortical microstructure in the living human brain. This project uses 7 Tesla MRI to describe the microstructural changes of the motor cortex in ALS patients, and to relate them to behavioral phenotypes and individual pathogenesis. This allows novel insights into the pathophysiology of ALS, and may advance the development of biomarkers that can predict individual trajectories of the disorder.

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