Viral infections can lead to a misdirected autoimmune response, in which the antibodies attack the own body (called anti-PF4 antibodies). They activate blood platelets and trigger life-threatening blood clots, e.g. in the brain. People of all ages can be affected, from young children to the elderly. Patients need to be diagnosed as quickly as possible to rapidly start treatment. This project aims to identify the mechanisms of disease development at a molecular level. In addition, patients will be systematically followed up in a long-term study in order to learn more about the course of this disease. The results of this study will improve diagnosis and treatment of virus-associated blood clots in the future.

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