Brain
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Sensing in motion - The role of sensory systems in cortex-basal-ganglia circuits of movement disorders patients
Funding line:
Else Kröner Clinician Scientist Return-To-Work Grant

Dr. Roxanne Lofredi conducting cortex basal ganglia connectivity analyses.
(© Wolf-Julian Neumann)
Parkinson's syndrome affects millions worldwide, causing movement disorders such as slowness, tremors, and gait instability. Over 70% of patients also experience sensory disturbances, including pain, abnormal sensations, loss of smell, visual impairments, and hallucinations. These significantly reduce quality of life, yet effective treatments are still lacking. This research project aims to precisely map the underlying brain networks. Using data from large cohorts of participants, including brain imaging and neuronal activity, circuits will be mapped with unprecedented spatial and temporal resolution. This could pave the way for targeted neurostimulation tailored to individual symptoms.
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