Transcatheter aortic valve implantation (TAVI) has become the standard procedure for patients aged 75 and older with aortic valve stenosis (AS). The gold standard for ruling out coronary artery disease (CAD) before TAVI is invasive coronary angiography. However, the exclusion of relevant CAD is often already achieved during the pre-TAVI evaluation using CT (CT). Given the residual risk of complications from invasive coronary angiography, the associated resource consumption, and its redundancy when significant coronary stenosis has already been excluded by TAVI-CT, the necessity of the procedure is being questioned. This study aims to investigate the benefit of a CT-centered diagnostic algorithm for ruling out significant CAD before TAVI.

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