Other
|

Mechanism of small fiber pathology in fibromyalgia syndrome

Institution: Department of Neurology, University of Würzburg
Applicant: Univ.-Prof. Dr. med. Nurcan Üçeyler, MHBA
Funding line:
First and Second Applications
Corneale confokale microscop (CCM) is a novel method to non-invasively investigate corneal innervation as a test for small fiber pathology.
Corneale confokale microscop (CCM) is a novel method to non-invasively investigate corneal innervation as a test for small fiber pathology.
(© Department of Neurology, University of Würzburg, Photgrapher: Brigitte May)

Fibromyalgia syndrome (FMS) is associated with chronic widespread pain. The reason for pain in FMS is unknown. We have shown that the so called small nerve fibers are impaired in subgroups of patients with FMS. Small nerve fibers are responsible for the conduction of pain. In our current project, we are investigating the extent and pattern of small nerve fiber damage in a large group of FMS patients compared to healthy controls. Our aim is to identify signatures and patterns that can be used to diagnose FMS patients and to find novel targets for analgesic against pain in FMS.   


Here you can get further information.