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Mechanism of small fiber pathology in fibromyalgia syndrome
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First and Second Applications
Fibromyalgia syndrome (FMS) is associated with chronic widespread pain. The reason for pain in FMS is unknown. We have shown that the so called small nerve fibers are impaired in subgroups of patients with FMS. Small nerve fibers are responsible for the conduction of pain. In our current project, we are investigating the extent and pattern of small nerve fiber damage in a large group of FMS patients compared to healthy controls. Our aim is to identify signatures and patterns that can be used to diagnose FMS patients and to find novel targets for analgesic against pain in FMS.
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