Light in - Sound out. New non-invasive biomarkers in pediatrics

Project start
Institution: Kinder- und Jugendklinik, Universitätsklinikum Erlangen
Applicant: Ferdinand Knieling
EKFS funding line: Else Kröner Memorial Fellowship
Optoacoustic in the paediatric experimental and translational imaging laboratory

Restricted diagnostic and therapeutic possibilities in chronically progressive hereditary diseases often result in a significantly reduced life expectancy of these young patients. New gene therapy approaches for Duchenne type muscle disease offer great hope, but no diagnostic methods are yet available to measure possible changes or response. Multispectral optoacoustic tomography (MSOT), a light- and sound-based imaging technology, could make it possible to detect molecular changes within a few seconds. The physician could thus detect the progression of the disease or a therapeutic response completely non-invasively and more accurately than before.    

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The latest press release can be found here.