Immunooncology and local interventions (IOLIN)

Project start
Institution: Klinikum der Ludwig-Maximilians-Universität München
Applicants: Prof. Dr. Sebastian Kobold (Speaker), Prof. Dr. Kirsten Lauber (deputy speaker), Prof. Dr. Dr. Michael von Bergwelt (deputy speaker)
EKFS funding line: Else Kröner Research School
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Immunotherapies can help many. However, a significant number of patients will not benefit from these. A major reason for treatment failure is the suppressive tumor environment. Oncologists are more and more making use of local treatments for metastasis (surgery, radiotherapy, radiology) which appear to have an important immunological impact. Along these lines, such local interventions are predestined for combinations with immunotherapies. This is the focus of IOLIN which aims at generating evidence for the synergy of such combined modalities to the benefit of cancer patients.

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