Goal of the project is the development of a non-invasive biosignature for the chronic rhinosinusitis without polyps. The pathophysiology of the disease will be investigated and a model for monitoring disease severity will be developed.
Potential protein biomarkers will be identified using a multiplexed approach and molecular biological validation methods. Due to the non-invasive design a painless and repetitive sampling is possible. A prospective study will be performed and it will be validated if the biosignature can monitor disease severity and therapeutic effects.
Here you can find further information.