Immune System

Deciphering shared tumoral and neural immunity in human paraneoplastic neurological syndromes: a systems immunological approach

Institution: Department of Neurology, Heinrich Heine University of Düsseldorf
Applicant: Dr. Saskia Räuber
Funding line:
Else Kröner Memorial Fellowships

The immune system is constantly working to prevent the spread of cancer cells and the development and progression of tumors. However, this intended immune response can be misdirected and cause neurological symptoms. Such diseases, known as paraneoplastic neurological syndromes (PNS), can affect different parts of the nervous system.
The aim of the project is to use modern immunological techniques to gain a deeper understanding of PNS and also fundamental insights into the behavior of the immune system in cancer. In addition to the early diagnosis and treatment of PNS, the project will also contribute to the diagnosis and treatment of early-stage cancer.