Chest Area

Catheter Ablation for atrial fibrillation in patientS with end-sTage heart faiLure and Eligibility for Heart Transplantation (CASTLE-HTx)

Institution: Clinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen
Applicants: Prof. Dr. Christian Sohns, Prof. Dr. Philipp Sommer, Dr. Vanessa Sciacca
Funding line:
Key Projects

This translational project investigates cahteter ablation of atrial fibrillation (AF) in patients with terminal heart failure while and before being listed for heart transplantation. AF is associated with higher morbidity and mortality. Catheter ablation of AF is an effective and safe therapy for patients without heart failure. For patients with advanced heart failure and AF no evaluated therapy exists until today. These patients might not gain access to ablation as a therapy that might avoid or postpone heart transplantation. The present study aims at investigation of efficacy and feasibility of ablation in patients with AF and terminal heart failure.

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