Neurogenesis in epilepsy of infectious etiology

Institution: Institut für Pharmakologie und Toxikologie, Fachbereich Veterinärmedizin, Freie Universität Berlin
Applicant: Prof Sonja Bröer, PhD
Funding line:
First and Second Applications

Epilepsies are among the most common neurological diseases worldwide. A high-risk event for seizures is an infection of the brain, although very little is known about the mechanisms of seizure development. The team is investigating whether infection-induced seizures could change the birth and maturation of nerve cells (neurogenesis) and thus contribute to the development of chronic epilepsy or cognitive impairment. In this project, initial insights into the time course of neurogenesis, as well as the fate of these cells after an infection are going to be collected. The results can be used to develop treatments that prevent or modify the long-term pathological consequences of infection.

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