Currently funded projects

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GRK5 plays a crucial role in the development of dependence and addiction after Morphine treatment.

Role of GRK5 in development of opioid dependence

Institution: Institute for Pharmacology and Toxicology, Jena University Hospital
Applicant: Dr. Andrea Kliewer
EKFS funding line: first application

Autoantibodies in Neuromyelitis optica spectrum disorders.

Beyond Aquaporin and MOG- Novel brain reactive antibodies and B cell responses in Neuromyelitis optica spectrum disorders

Institution: Institute of Clinical Neuroimmunology
Biomedical Center of the Ludwig Maximilian University of Munich
Applicant: Simone Mader
EKFS funding line: first application

In vivo high field MRI (left) and ultramicroscopy images (right) of the cleared brain shows the extent of tumor cell infiltration of S24 glioma cells (red). The microvasculature is stained with lectin-FITC (green).

Imaging of immune responses and tumor cell invasion in glioma models

Institution: Universitätsklinik Heidelberg – Deutsches Krebsforschungszentrum
Applicant: Dr. med. Michael Breckwoldt, Ph.D.
EKFS funding line: first application

Homoarginine supplementation reduces infact size (white) in experimental stroke models (left) and higher homoarginine levels in patients are associated with increased survival rates after stroke (right)

Clinical and experimental evaluation of homoarginine in stroke treatment

Institution: Department of Neurology, University Medical Center Hamburg-Eppendorf
Applicant: PD Dr. Chi-un Choe
EKFS funding line: Else Kröner-Exzellenzstipendium

Staining of cerebellar tissue with a monoclonal  GAD-antibody

B-cell-mediated immune response in GAD-antibody-associated neurological disorders

Institution: Institute of Clinical Neuroimmunology, University Hospital and Biomedical Center, Ludwig-Maximilians University Munich
Applicant: Franziska Thaler
EKFS funding line: first application

Changes of brain function, brain structure and brain perfusion in subjects with induced hyperthyroidism

Influence of thyroid hormones on brain, cognition and behaviour

Institution: Clinic for Neurology, University Hospital Schleswig-Holstein, Campus Lübeck
Applicant: Dr. med. Anna Göbel
EKFS funding line: Else Kröner-Memorial-Stipendium

Key aspects of the CRPS-GMI study

Pathophysiology of the complex regional pain syndrom (CRPS) and effect of an innovative therapeutic approach

Insitution: University Medicine Greifswald
Applicant: Dr. med. Sebastian Strauss
EKFS funding line: first application

Timo Uphaus in front of a surgical microscope

Common pathology-derived biomarker/therapy development in neuroinflammation and stroke

Institution: University Medical Center of the Johannes Gutenberg University Mainz
Applicant: Timo Uphaus
EKFS funding line: Else Kröner-Memorial-Stipendium

TMS Mapping Ergebnis

Resection of initially non-resectable brain tumors after detection of functional reorganization of the motor cortex with navigated transcranial magnetic stimulation

Institution: Charité Universitätsmedizin
Applicant: PD Dr. Thomas Picht
EKFS funding line: key project

By using specific peptides binding of the enzymes CK1δ and CK1ε to tau and/or the amyloid precursor protein can be blocked and characteristic damage caused by aggregation of tau and amyloid-beta can be reduced.

Development of therapeutic peptides for the treatment of Alzheimer’s disease

Institution: Ulm University Hospital, Department for General and Visceral Surgery
Applicant: Dr. rer. nat. Joachim Bischof
EKFS funding line: first application