Currently funded projects

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The Relaxin Receptor 1 for Treatment of Heart Failure

Institution: Medizinische Klinik (Krehl-Klinik), Zentrum für Innere Medizin, Klinik für Kardiologie, Angiologie und Pneumologie, Innere Medizin III, Heidelberg
Applicant: Prof. Dr. med. Philip Raake
EKFS funding line: Translational Research

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Phase I clinical trial of intracranial injection of CAR-engineered NK cells in patients with recurrent HER2-positive glioblastoma

Institution: Georg-Speyer-Haus, Institut für Tumorbiologie und experimentelle Therapie, Frankfurt am Main
Applicant: Prof. Dr. Winfried Wels
EKFS funding line: Translational Research

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Development of a targeted treatment concept against transforming HPV infections

Institution: Abteilung für Angewandte Tumorbiologie (ATB), Pathologisches Institut Universitätsklinikum Heidelberg u. Klinische Kooperationseinheit (KKE) Angewandte Tumorbiologie Deutsches Krebsforschungszentrum (DKFZ)
Applicant: Dr. Elena-Sophie Prigge

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LipOra-micelle technology for advanced oral peptide drug delivery

Institution: Heidelberg University Hospital, Department of Clinical Pharmacology and Pharmacoepidemiology
Applicant: Prof. Walter E. Haefeli, MD, FBPhS
Co-applicants: Dr. Max Sauter, PhD, Dr. Philipp Uhl, PhD
EKFS funding line: Translational Research

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Leukocyte counts in capillary blood micro-samples based on targeted analysis of DNA methylation with digital droplet PCR - “Prick-Me”

Institution: Uniklinik RWTH Aachen Abteilung Stammzellbiologie und Cellular Engineering (AG Wagner)
Applicants: Dr. rer. nat. Mariangela Sociale
(Co-applicant: Prof. Dr. Dr. Wolfgang Wagner)
EKFS funding line: Translational Research




Image: magnetic resonance (MR)- positron emission tomography (PET

Anthropomorphes 4D Phantom

Institution: Arbeitsgruppe Electronic & Embedded Systems Development Lab Deutsches Krebsforschungszentrum (DKFZ)
Applicant: Steffen Seeber
EKFS funding line: Translational Research

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A quality-managed software platform for quantitative microstructural tissue characterization using diffusivity imaging for early detection of cancer (Acronym: ARGOS-Imaging)

Institution: Universitätsklinikum Erlangen
Applicant: PD Dr. med. Sebastian Bickelhaupt
Co-applicant: PD Dr. med. Klaus Maier-Hein (Deutsches Krebsforschungszentrum Heidelberg)
EKFS funding line: Translational Research


Image: Preparation of the implant

Reconstruction of Lower Urinary Tract with vascularized "small intestinal submucosa" (BioVaSc-TERM®), Acronym: UroVasC

Institution: Fraunhofer-lnstitut für Silicatforschung ISC
EKFS funding line: Translational Research

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The Role of Necroinflammation in Preclinical Kidney Xenotransplantation

Institution: Universitätsklinikum Carl Gustav Carus, Dresden
Applicant: Prof. Dr. med. Andreas Linkermann
EKFS funding line: Translational Research

BsAb directed to PSMA and CD3 recruit T cells against tumor cells (A). To avoid “off target” activation and thus side effects (B), expression of the selected target antigen should be restricted to tumor cells.

Drug substance production of the bispecific PSMAxCD3 antibody CC-1 to enable the conduct of a clinical study in patients with squamous cell carcinoma of the lung

Institution: Klinische Kooperationseinheit Translationale Immunologie, Deutsches Konsortium für Translationale Krebsforschung (DKTK), Deutsches Krebsforschungszentrum (DKFZ), Department für Innere Medizin, Universitätsklinikum Tübingen
EKFS funding line: Translational Research