Currently funded projects

Agonist-dependent activation of the tagged 2-adrenergic receptor. The regulation of the receptor can be analyzed by anti-tag antibody.

Localization and regulation of endogenous β2-adrenergic receptors

Institution: Jena University Hospital, Department of Pharmacology and Toxicology, Drackendorfer Straße 1, 07747 Jena
Applicant: Dr. rer. nat. Elke Miess
EKFS funding line: first application

Three-dimensional Structure of the Na+ -Pump NQR

Identification of new lead molecules for the inactivation of an essential Na+ pump in Gram-negative, multiresistant pathogens

Institution: Universität Hohenheim, Institut für Mikrobiologie
Applicant: Prof. Dr. Julia Fritz-Steuber
EKFS funding line: first application

Investigation of galectin-1-sugar-metabolome axis during healthy and preeclamptic pregnancies

REPRODOMICS project – Deciphering galectin-1 signalling in preeclampsia: insights from metabolomics

Institution: Charité – Universitätsmedizin Berlin, Experimental and Clinical Research Center (ECRC)
Applicant: Dr. Nancy Freitag
EKFS funding line: first application

"Podocytes are specialized epithelial cells of the glomerular filtration barrier (GFB)."

Human bioactive peptide based intervention strategies to treat proteinuria

Institution: Universitätsklinikum Erlangen, Medizinische Klinik 4
Applicant: Prof. Dr. Mario
EKFS funding line: first application

Data Analysis

Modulation of adipocytes vitality after autologous fat transplantation through repetitive leptin application

Institution: University Clinic of Leipzig, Department for Orthopaedics, Traumatology and Plastic Surgery
Applicant: Dr. med. Jeannine Schreiter
EKFS funding line: first application

Migrationsassay (Scratchassay mit hitzegeschädigten Fibroblasten)

Charakterisierung der zytoprotektiven und wundheilungsfördernden Wirkung des Growth/Differentiation Factor 5 (GDF-5) in einem in vitro Zellkulturmodell sowie ex vivo in einem Verbrennungsmodell der menschlichen Haut

Institution: Klinik für Plastische Chirurgie, Krankenhaus Merheim, Lehrstuhl der Universität Witten Herdecke
Applicant: PD Dr. Jennifer Schiefer
EKFS funding line: first application

To elucidate the binding properties of desmosomal cadherins we use atomic force microscopy.

Effects of Plakophilins on binding properties of desmosomal cadherins

Institution: Anatomische Anstalt, LMU München
Applicant: Franziska Vielmuth, Jens Waschke
EKFS funding line: first application

The pro-apoptotic BCL-2 proteins BAX or BAK (blue) associate with the outer mitochondrial membrane (OMM) of human cells.

BCL-2 protein regulation by altered glucose metabolism in tumor cells

Institution: Institute for Biochemistry and Molecular Biology, University of Freiburg, 79104 Freiburg, Germany
Applicant: Frank Edlich
EKFS funding line: key project

Tissue replacement of damaged joints with human bone marrow-derived stem cells is a promising therapeutic option in regenerative medicine.

Influence of gender, age and lifestyle of the bone marrow donor on the characteristics of bone marrow derived mesenchymal stem cells

Institution: Trauma Department, Hannover Medical School
Applicant: Dr. Sandra Noack
EKFS funding line: first application

Localisation of Wt1 protein (rot) in the nuclei of oviducts of mice (left) and men (right). E-Cadherin (green) marks oviductal tissue; cell nuclei are stained in blue.

A role for the Wilms tumour suppressor gene Wt1 in female fertility

Institution: Leibniz-Institut on Aging – Fritz Lipmann Institute (FLI)
Applicant: Christoph Englert
EKFS funding line: first appliccation