May 2023: $$ Cancer neuroscience: State of the field, emerging directions

Journal: Cell 2023
Author: Varun Venkataramani
Institution: University Clinic Heidelberg
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Project description:

The nervous system is a critical regulator in our bodies, influencing not just our development but also the behavior of cancers. This system orchestrates the formation of organs during our growth, maintains a balanced internal environment, and allows for adaptability throughout our lives. Similarly, it has a role in managing various aspects of cancer, from its onset to its spread.

The nervous system is a critical regulator in our bodies, influencing not just our development but also the behavior of cancers. This system orchestrates the formation of organs during our growth, maintains a balanced internal environment, and allows for adaptabiliRecent scientific discoveries have shown that nerve cells can directly or indirectly communicate with cancer cells. This interaction can have a profound impact on how cancer develops, grows, and responds to treatments. It can even affect our body's natural defenses against cancer.y throughout our lives. Similarly, it has a role in managing various aspects of cancer, from its onset to its spread.

This perspective article aims to provide a roadmap for the emerging field of cancer neuroscience. It highlights the importance of understanding the intricate relationship between the nervous system and cancer as a potential cornerstone for future cancer therapies. By delving into this interdisciplinary area, we can unlock new avenues for research and treatment strategies, thereby adding a significant new dimension to the fight against cancer.

Publication:

Frank Winkler, Humsa S. Venkatesh, Moran Amit, Tracy Batchelor, Ihsan Ekin Demir, Benjamin Deneen, David H. Gutmann, Shawn Hervey-Jumper, Thomas Kuner, Donald Mabbott, Michael Platten, Asya Rolls, Erica K. Sloan, Timothy C. Wang, Wolfgang Wick, Varun Venkataramani and Michelle Monje. Cancer neuroscience: State of the field, emerging directions, Cell. April 2023.

Paper: https://www.cell.com/cell/pdf/S0092-8674(23)00104-6.pdf
 

 

Submitting the Paper of the Month:

Else Kröner-Fresenius-Stiftung is using the series “Paper of the Month” to report in an exemplary and hot-off-the-press style on the outstanding work being done by the scientists it supports. We regularly present publications which have recently appeared in especially renowned journals, have emerged from foundation funding and been given appropriate acknowledgment. This is done in the respective categories “Original Paper” and “Review”. In the case of each of these publications, the first author and/or senior author are being funded by the foundation.

We invite all project managers, fellowship recipients and members of graduate study programs to send their work in accordance with the stated criteria as proposal for Paper of the Month to Ms. Anne Asschenfeldt (a.asschenfeldt@ekfs.de).
 

More Paper of the Month can be found here.

Anne Asschenfeldt
Anne Asschenfeldt
Scientific Funding: Ongoing Project Funding and Fellowships